Endocrine Abstracts

The neurotransmitter Serotonin (5-hydroxytrympatmine (5-HT), influences hormone secretion from human and rodent islets of Langerhans. Given its confirmed local production in the insulin producing beta (β)-cells, this monoamine has been shown to modulate insulin secretion by both intra- and extracellular mechanisms. However, the precise mechanisms by which 5-HT its effects on insulin release and whole-body glucose metabolism is yet to be fully understood. Fourteen differen...